Oxygen Toxicity- Clinical application of Oxygen, its effective and toxic doses

Oxygen is vital to sustaining life. However, breathing oxygen at higher than normal partial pressure leads to hyperoxia and can cause oxygen toxicity or oxygen poisoning. The clinical settings in which oxygen toxicity occurs is predominantly divided into two groups; one in which the patient is exposed to very high concentrations of oxygen for a short duration, and the second where the patient is exposed to lower concentrations of oxygen but for a longer duration. These two cases can result in acute and chronic oxygen toxicity, respectively.

Human hand mannual Strangulation (throttling), Suicide by hanging and ligature mark explained by SC

“ligature mark brown coloured encircling whole of neck measuring 39 cms, all round the neck, ½ cms. on the sides and back and 2 cms. in the front of the neck anteriorly placed on the thyroid cartilage horizontally, margins were irregular, echymosed and base of ligature was dry and parchment like and membranous. On cut Section there were multiple echymotic spots on subcutaneous tissue and muscles. Thyroid cartilages was broken cricoid cartilage was also broken

Hemodynamic stability of trauma patients

The assessment of the hemodynamic (HD) status in blunt trauma patients is vital for early identification and timely management of a potential hemorrhage to keep the time between injury and intervention to a minimum. In order to improve trauma care furthermore, evidence-based practice guidelines are designed and implemented in every hospital. These management schemes are often based on the presence or absence of HD stability, proposed by the American College of Surgeons Advanced Trauma Life Support (ATLS) guidelines .

Treatment Guidelines for Antimicrobial Use in Common Syndromes-ICMR 2019

Klebsiella pneumoniae has emerged over the last few years as a highly resistant pathogen with up to 50% resistance to carbapenems and rapidly increasing resistance to polymyxins. In addition, methicillin resistance in Staphylococcus aureus is seen in up to 30% of S. aureus isolates nationally. It is well documented that antibiotic abuse is one of the major drivers of antibiotic resistance and thus optimising usage of antibiotics is the need of the hour.