The composition and physiological purpose of menstruation
Menstruation serves to eliminate bacteria from the uterus, influenced by various microorganisms from the lower genital tract. Menstrual blood comprises blood, vaginal fluid, and endometrial fluid, with a unique protein composition. Contamination with pathogens like Escherichia coli can initiate pelvic inflammation, highlighting significant biological and microbial processes during menstruation.
Menstruation evolved to rid the uterus of bacteria. Due to the mixed nature of menstrual blood, it is difficult to know if the biological processes common to blood and menstrual blood, and vaginal fluid and menstrual blood. The menstrual cycle is a complex, finely orchestrated series of cellular, physiological, and biochemical changes under precise endocrine control that routinely builds a rich endometrial lining in constant anticipation of blastocyst implantation. A study shows that the woman’s lower genital tract is constantly exposed to various microorganisms, which could infect the upper genital tract through direct migration. It is found that, as normal microbial flora in the vagina, some gram-negative bacteria infect the uterine wall after ascending migration from the vagina to contaminate menstrual blood, consequently resulting in the accumulation of endotoxin in the menstrual/peritoneal fluid and initiation of pelvic inflammation.
Menstrual blood is composed of three distinct body fluids: blood, vaginal fluid, and the cells and fluid of the late secretory phase of the uterine endometrial lining, which is shed during menstruation.
Proteins are shared between venous and menstrual blood, while 513 proteins (48%) are unique to menstrual blood. A comparison of menstrual blood to vaginal fluid shows 388 shared proteins, while 673 (63%) are unique to menstrual blood. When all three body fluids are compared, menstrual blood contained a total of 385 proteins (36% of total) not found in vaginal fluid or venous blood.
Blood and menstrual blood share two processes: death and establishment of localization, while vaginal fluid and menstrual blood also share two common processes: biological adhesion and developmental process. It should be noted that neither metabolic nor cellular processes, which involve the greatest percentage of proteins in blood, were identified in menstrual blood, and that locomotion is the sole biological process identified only in menstrual blood. The menstrual blood is highly contaminated with Escherichia coli, and the endometrial samples[blood] are colonized with other microbes.
NB:-Â The Purpose of this article is legal only, and we accept the premise that Holiness is different from Hygiene.
